Thursday, September 23, 2021

Emcizumab- new bispecific antibody for hemophilia A

 Emcizumab


The new kid on the block for hemophilia patients.


Key points:

1. This is a bispecific antibody that restores the function of factor 8. It binds to factors 9 and 10, and activates the clotting.

2. Subcutaneous, can be given every 2-4 weeks.

3. Injection site pain, swelling. Risk of clotting in those with previous factor 8 inhibitors.

4. Do not combine with APCC.

No comments:

Post a Comment

Primary CNS lymphoma

 Reference: Annals of Oncology  June 2024 ESMO guidelines Diagnosis  Recommendations • Contrast-enhanced cranial MRI is the recommended imag...