Ref: NCCN
If RS>26 --> chemo in all comers
Premenopausal women
1. If node neg and RS < 15--> no chemo per TAILOR X
2. If node neg and RS 16-25--> some chemo benefit but possibly due to OFS in women less than 50 yr
3. If node positive and RS < 26--> some chemo benefit per PONDERRX
Post menopausal women
If RS< 26, even with 1-3 LN, ok to omit chemo.
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