IMPEDE or SAVED score can be used.
SAVED score 3 or higher --> use Lovenox 40 mg daily, OR Warfarin INR 2-3, Rivaroxaban 10 mg or Eliquis 2.5 mg BID
Otherwise Aspirin 325 mg or 81 mg
SAVED score
- Prior VTE= 3
- High dose dex ( > 160 mg per cycle)= 3
- Prior surgery in the last 3 m= 2
- Low dose dex( 120-160/ cycle)= 2
- Age > 80 yr= 1
- Asian race= negative 3
Does the patient have cytopenias? Bleeding risk? Renal or liver dysfunction? Already on anticoagulation or another reason to be on anticoagulation? Hx of HIT. Any drug interactions with DOAC or Lovenox?
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