Tuesday, October 24, 2023

NCCN adjuvant and NACT lung

 For stage II and IIIA- get PDL1, EGFR, ALK

If EGFR neg--> NACT platinum doublet with nivo 3 cycles

Adjuvant 

If EGFR, ALK neg, and PDL1 0- after adjuvant chemo, pembro

If EGFR positive, after chemo, osimertinib for 3 yr

If EGFR and ALK neg, PDL1 > 50, can consider atezo although pembro would be fine


For ALK mutation positive--> after 4 cycles chemo, no IO. Can consider clinical trial.

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