For stage II and IIIA- get PDL1, EGFR, ALK
If EGFR neg--> NACT platinum doublet with nivo 3 cycles
Adjuvant
If EGFR, ALK neg, and PDL1 0- after adjuvant chemo, pembro
If EGFR positive, after chemo, osimertinib for 3 yr
If EGFR and ALK neg, PDL1 > 50, can consider atezo although pembro would be fine
For ALK mutation positive--> after 4 cycles chemo, no IO. Can consider clinical trial.
No comments:
Post a Comment