1. Thalassemia trait does not cause spherocytes on smear
2. High activity low titer antibodies can cause neg Coomb's. Other causes include Ig A type Ab.
3. Folate def presents with elevated homocysteine levels, whereas MMA is elevated in B12 def.
4. Copper deficiency questions-- hx of malabsorption or small bowel surgery/ gastric bypass surgery. Check ceruloplasmin levels
5. Lead poisoning in the vignette- hx of pica, microcytic anemia due to iron def seen in lead poisoning
6. Rasburicase can lead to hemolytic anemia esp due to G6PD --> drug induced hemolytic anemia
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